A Cambridge Scientific Innovations company

The CambTEK RES

Applications

RES20140801 Dilution Reproducibility Test

The CambTEK® Rapid Extraction System (RES) was used to automate the process of sample preparation for subsequent Ultra High Performance Liquid Chromatography (UHPLC) analysis of extracts from solid dosage forms (SDF). A series of paracetamol extracts were produced within 1:200 range of automated dilutions. Each sample was analysed by the Agilent 1290 Infinity® Quaternary LC system. 

The resulting data shows the excellent linearity of the RES sample preparation system. The automated dilutions are all within ASTM Class A dispensing specifications. The data is compliant with the requirements for sample preparation enabling quantitative analysis of active product ingredients (API) in Quality Assurance/Quality Control (QA/QC) environments. 

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RES20140804 Carryover Test

The CambTEK® Rapid Extraction System (RES) can be used to automate the process of sample preparation. In particular it is designed to automate the testing of products of solid dosage forms (SDF), such that might be required for Quality Assurance and Quality Control (QA/QC), content uniformity, or stability testing. To ensure accurate results are achieved, a Carryover test is an essential part of the Performance Qualification (PQ) of the system. In this Performance Qualification test, absorbance values measured in 6 BLANK solutions, following acetaminophen triplicate solutions of 50 to 1000 (±0.0005) mg sample mass range, were all below the detection limit. 

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RES20141201 Carryover Test

The CambTEK® Rapid Extraction System (RES) can be used to automate the process of sample preparation. In particular it is designed to automate the testing of products of solid dosage forms (SDF), such that might be required for Quality Assurance and Quality Control (QA/QC), content uniformity, or stability testing. To ensure accurate results are achieved, a Carryover test is an essential part of the Performance Qualification (PQ) of the system. In this Performance Qualification test the experimental detection limit was 0.00013 mg/mL of acetaminophen. The measured peak areas of the six blank solutions were all below the detection limit. 

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RES20150101 Reproducibility Test

The CambTEK® Rapid Extraction System (RES) can be used to automate the process of sample preparation. In particular it is designed to automate the testing of products in solid dosage forms (SDF), by dissolving them in a suitable extraction solvent with Class A dispensing accuracy and a full audit trail via bar codes. Such samples are typically required for Quality Assurance and Quality Control (QA/QC), content uniformity and stability testing. 

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The RES brochure

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